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Prevalence of Chronic Gastrointestinal Symptoms in Children with Autism and Autistic Spectrum Disorders

Cynthia A. Molloy

Cincinnati Children’s Hospital, USA, Cynthia.molloy{at}chmcc.org

Patricia Manning-Courtney

Cincinnati Children’s Hospital, USA

The purpose of this study was to estimate the prevalence of chronic gastrointestinal symptoms in a general population of children with autism or autistic spectrum disorder (ASD). The study site was a clinic specializing in ASD in a large pediatric medical center serving a 10 county area in the midwestern USA. In a sample of 137 children, age 24-96 months, classified as having autism or ASD by the Autism Diagnostic Observation Schedule-Generic, 24 percent had a history of at least one chronic gastrointestinal symptom. The most common symptom was diarrhea, which occurred in 17 percent. There was no association between chronic gastrointestinal symptoms and a history of developmental regression. The potential phenotypic association between autism and gastrointestinal symptoms is discussed.

Key Words: autism • autism spectrum disorder • chronic diarrhea • gastrointestinal

Autism, Vol. 7, No. 2, 165-171 (2003)
DOI: 10.1177/1362361303007002004


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